Posted 3/16/07 |
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| TOPIC: | Botanicals, HIV, and Immune Support | |||||||
| DESCRIPTION: | Overview (Adapted from NYBC's Managing HIV Symptoms and Drug Side Effects) | |||||||
| PREFACE: | General cautionary note: Many natural therapies that are currently freely available on the commercial market work through enhancing normal bodily processes and mechanisms, such as enhancement of cardiovascular, immune, or liver functions. Normally, such effects are highly desirable and beneficial. However, caution is advised: therapies that enhance liver function can dramatically alter the level of conventional medications that occur in the blood, thereby potentially affecting their efficacy.
When starting on natural therapies, especially those affecting the liver, it is wise to consult with a qualified natural health care consultant. At the end of this document you will find a list of referrals for natural healthcare providers who can help you make informed decisions about your health management strategy. |
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| INTRODUCTION: |
In addition to direct therapies used for the reduction of viral loads and improvement of immune deficiency syndromes, there are numerous botanical and nutritional therapies that can be used to support secondary conditions and symptoms that are common among those with immunodeficiency syndromes. Following is a review of some of these therapies including an overview of primary categories of nutrients that are key to maintaining health. It is important to remember that herbal medicines are used within the context of a comprehensive healing program and, when used by experts, are typically formulated according to the specific needs of the patients. For expert advice regarding herbal medicines, consumers and patients should seek the assistance of a qualified herbal health care practitioner. There are numerous botanical therapies that are specific for enhancing immune function. These botanicals can be used alone to enhance immune resistance as well as be used in conjunction with conventional anti-HIV therapies. Many of these botanicals are also used to enhance immune resistance in those undergoing conventional therapies for cancer. Most have specific antitumor and antiviral activity as well as general and broad ranging immune enhancing effects such as restoration of hematopoiesis, enhancement of macrophage count and activity, increase in CD4s, and improved ratios of CD4s/CD8s. Most also have liver supportive effects in those with chronic hepatitis. |
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| BOTANICAL: | Astragalus Root (Astragalus membranaceus): Astragalus has broad spectrum immune modulating activity and is the primary immune supportive botanical used in Chinese medicine.
Numerous immune-related mechanisms of action have been reported including: improved T-cell activity, generation of blood cells (hematopoiesis), increased macrophage and natural killer cell activity, induction of interferon, and induction of tumor necrosis factor. Clinically it is used to support immune resistance in subjects undergoing conventional cancer and HIV therapies. It is specifically used in the restoration of immunocompetence after conventional chemotherapies. Astragalus has also been shown to have hepatoprotective and antioxidant activity (increases glutathione) and is widely used in the treatment of chronic hepatitis. In healthy individuals, it is the most specific botanical used in the prevention of infections. It is best used in conjunction with other immunomodulating botanicals such as atractylodes and ligustrum. |
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| RELATED LINKS: |
Read more about astragalus on NYBC's Astragalus Fact Sheet
NYBC Store: Astragalus (MMS) Each bottle, 100 capsules. Each capsule, 470 mg of astragalus root |
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| BOTANICAL: | Atractylodes Root: Atractylodes has been reported to increase phagocytic action of the reticuloerndothelial system, increase white blood cell count, and enhance cellular immunity. It is one of the primary botanicals for increasing immune resistance. It is best combined with other tonics such as astragalus and ligustrum. | |||||||
| BOTANICAL: | Echinacea: Echinacea is the primary immune stimulating botanical used in western herbalism. It has a specific action of enhancing macrophage activity, acting as an anti-inflammatory, through the inhibition of hyaluronidase (an enzyme associated with inflammation), and exhibiting antiviral activity against numerous viruses.
It is most widely used for the prevention and treatment of colds, influenzas (flu), and systemic infections, though clinical data regarding its efficacy is mixed. Three primary species are used: E. angustifolia, E. pallida, and E. purpurea. Each are used equally in modern practice. Most herbalists prefer liquid hydro-alcohol extracts for rapid absorption and prolonged shelf life. |
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| RELATED LINKS: |
Read more about echinacea on NYBC's Echinacea Fact Sheet
NYBC Store: Echinacea (MMS Pro) Each bottle, 100 capsules. Each capsule, 400 mg of the stem, leaf and flower of Echinacea purpurea. |
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| BOTANICAL: | Indolplex (diimdolylmethane [DIM]) A substance derived from broccoli that helps maintain healthy estrogen metabolism in both men and women and appears to help the body eradicate cancer cells.
Suggested for: women on estrogen replacement therapy, men with increasing prostate antigen levels, and both men and women who are aging. |
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| BOTANICAL: | IP 6 (Inositol hexaphosphate , a.k.a. phytic acid) A substance found in soybeans and rice bran that appears to enhance natural killer cell (NK) activity and may be protective against cancer and certain toxins. It also seems to be useful in lowering blood fats, including cholesterol. | |||||||
| CAUTIONS: | IP 6 can decrease absorption of iron, zinc, manganese and other minerals, so take your minerals separately maybe even skipping a day. Since it helps get rid of excess iron, it’s useful for hepatitis, but bad for iron-deficiency anemia. | |||||||
| BOTANICAL: | Ligustrum Fruit (Ligustrum chinensis): Has been shown to increase white blood cell count in those with leukopenia due to chemo and radiation therapies and increase general immune resistance.
It is one of the primary botanicals used to support immune resistance while undergoing conventional therapies for cancer. Best used in conjunction with other immune modulating botanicals such as astragalus, atractylodes, and schisandra. |
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| BOTANICAL: | Maitake Mushroom (Grifola frondosa): Maitake is one among a number of medicinal mushrooms widely used in the treatment and prevention of cancer.
The primary actions of maitake include: increased secretion of interleukin- and 2, which in turn stimulate the body’s cancer fighting mechanisms; and increased macrophage, natural killer cell, and CD4 activity. These activities are reportedly due to maitake’s rich concentration of the immunomodulating polysaccharide beta-glucan. According to Dr. Hiroaki Nanba, a Japanese researcher who discovered this fraction in maitake, the mushroom works in four ways to help in the treatment and prevention of cancer:
A limited number of clinical reports showing positive effects used a variety of dosages including a low of 25 mg and a high of 150 mg of beta-glucan fraction. Some of the cases included an additional 6 g of maitake fruiting body. A standard dose has been recommended as 1 mg of beta-glucan fraction per kilo of body weight (approximately 70 mg for average male adult weight). |
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| BOTANICAL: | Schisandra Fruit (Schisandra chinensis): The primary importance of schisandra in supporting immune functions is its action as an adaptogen and enhancing energy production, endurance, and recovery from exertion.
It also exhibits anti-inflammatory and liver-protecting effects. It is best used in conjunction with other immune modulating botanicals such as astragalus, ligustrum, and atractylodes. |
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| CAUTIONS: | Schisandra may modulate cytochrome P-450 enzyme systems, and therefore, may alter the effectiveness of conventional medications affected by this system.
Consult a qualified health care professional when using schisandra in conjunction with conventional medications (see below). |
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| DISCLAIMER: | These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. | |||||||