Posted 3/16/07 |
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| NAME: | Glutamine | |
| DESCRIPTION: | Amino acid
L-glutamine is the most abundant amino acid in the body; it participates in many metabolic reactions in the body, and is predominantly synthesized and stored in skeletal muscle. L-Glutamine is classified as a semi-essential or conditionally essential amino acid - meaning that under normal circumstances, the body can synthesize sufficient amounts to meet physiological demands. However, there are conditions where the body cannot do so. L-glutamine has come to be regarded as one of the most important of the amino acids when the body is subjected to metabolic stress. Available by prescription, also — New York state Medicaid covers it, for example. |
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| FUNCTION: | Positively impacts gastrointestinal tract function - improving digestion and helping decrease intestinal permeability - boosting the digestive system's nutrient absorption.
Glutamine is used to treat “leaky gut” syndrome, which results when intestinal tissues are damaged. Glutamine is taken up in cells of the intestine and then oxidized, strengthening the overall structure. |
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| SOURCES: | Small amounts of free L-glutamine are found in vegetable juices and fermented foods, such as miso and yogurt. | |
| DOSAGE: | Typical doses for those with cancer, AIDS, trauma, burns, infections and other stress-related conditions range from 4 to 21 grams daily.
Also used for chemotherapy- or radiation-induced stomatitis: (inflammation of the mucous membrane of the mouth) doses of 2 to 4 grams twice daily or 2 grams four times daily - dissolved in water and used as a swish and swallow. |
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| DATA: | Glutamine, HIV meds, and diarrhea: Clinical studies have demonstrated that people with protease-inhibitor-caused diarrhea find relief using 30-40 grams per day: start with about 15 grams per day and increase the dose until the diarrhea is controlled. For those using the powder form, each kitchen teaspoon is about 5 grams. A daily maintenance dose is one teaspoon a day. Take three times per day before/after or at the very beginning of meals for it to work effectively. | |
| CAUTIONS: | Those with liver or kidney problems should exercise caution in the use of supplemental L-glutamine. | |
| FOR MORE INFORMATION: |
Physician's Desk Reference's entry on L-glutamine provides solid information.
Lyn Patrick, ND (Doctor of Naturopathy), in Alternative Medicine Review, offers a comprehensive and well-documented overview of the use of several supplements in "Nutrients and HIV: Part Three – N-Acetylcysteine, Alpha-Lipoic Acid, L-Glutamine, and L-Carnitine" |
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| RELATED PRODUCTS: |
Glutamine capsules(NYBC) Each bottle, 100 capsules. Each capsule, 500 mg
Glutamine Powder - bulk (NYBC) Each ziploc bag, 1,000 grams of powder ( 1 kilogram / 2.2 pounds). Each quarter kitchen teaspoon has 700 mg. |
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| PRODUCT NOTES: | Suggested use (of Glutamine Powder) is a quarter teaspoon (700 mg) in juice 1–3 times a day, between meals. However, some PWHIV are using a loading dose of up to 9 grams per day for a month to six weeks, and then tapering it down by 50% in the hopes of reducing infections, increasing absorption and lessening severe inflammation along the GI tract. Higher doses—up to 30+ grams per day—are being used for weight gain and/or very severe intestinal inflammation. Many mix their amino acid powders together or put them in their protein powder. | |
| DISCLAIMER: | These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. | |
